|
KMID : 0914820160160020078
|
|
Journal of the Korean Gastric Cancer Association
2016 Volume.16 No. 2 p.78 ~ p.84
|
|
|
Primary Tumor Resection and Survival in Patients with Stage IV Gastric Cancer
|
|
Fatma Yalcin Musri
Hasan Mutlu
Mustafa Karaa?ac
Melek Karakurt Eryilmaz
Seyda Gunduz
Mehmet Artac
|
|
|
Abstract
|
|
|
Purpose: The aim of this study was to determine whether surgical resection of the primary tumor contributes to survival in patients with metastatic gastric cancer.
Materials and Methods: A total of 288 patients with metastatic gastric cancer from the Akdeniz University, Antalya Training and Re-search Hospital, and the Meram University of Konya database were retrospectively analyzed. The effect of primary tumor resection on survival of patients with metastatic gastric cancer was investigated using the log-rank test. Kaplan-Meier survival estimates were calcu-lated. Multivariate analysis was performed using Cox proportional hazards regression modeling.
Results: The median overall survival was 12.0 months (95% confidence intewrval [CI], 10.4~13.6 months) and 7.8 months (95% CI, 5.5~10.0 months) for patients with and without primary tumor resection, respectively (P<0.001). The median progression-free survival was 8.3 months (95% CI, 7.1~9.5 months) and 6.2 months (95% CI, 5.8~6.7 months) for patients with and without pri-mary tumor resection, respectively (P=0.002).
Conclusions: Non-curative gastrectomy in patients with metastatic gastric cancer might increase their survival rate regardless of the oc-currence of life-threatening tumor-related complications.
|
|
|
KEYWORD
|
|
|
Stomach neoplasms, Surgery, Mortality
|
|
|
FullTexts / Linksout information
|
|
 
|
|
|
Listed journal information
|
|
  
|